Clinical Blogs — hyperpigmentation

When it comes to ingredients with strong supporting clinical data and variety of uses, vitamin B3 (niacinamide) is the one that is on the top of the list. It is one of the most versatile ingredients can be used in various skincare formulation with multiple benefits as a nutraceutical for our skin. Vitamin B3 is a multitask ingredient beneficial to skin health: Increases hydration: It strengthens the top layer of our skin (strata corneum) which is responsible for transdermal epidermal water loss (TEWL). B3 possesses antipruritic effect: enhances skin barrier protection by stimulating ceramide synthesis and stabilizing mast cells that...

Throughout my clinical practice, I have come across many clients with various skincare concerns. “What do you recommend for the dark spots on my face?” is one of the most common questions I got. Evening skin tone and reducing pigmentation are always in trend regardless of age and ethnicity. Before making any suggestion to my clients, gathering pertinent information and medical history that could potentially cause the problem is important. What are the stimulating factors? / How does hyperpigmentation occur? Melanocytes are skin cells that produce brown pigment (melanin) which is responsible for our skin color. If melanocytes increase melanin...

Lustra is one of the topical skin bleaching creams that contains hydroquinone (HQ) as the key ingredient. Hydroquinone is a clinically proven depigmenting agent that is used to lighten hyperpigmentation, or dark spots and patches, age spots, and freckles, by suppressing the melanocyte production by inhibiting tyrosinase (the enzyme that makes melanin).

Hyperpigmentation is a condition where areas of skin are darker in color as compared to the surrounding area of the skin. Major causes of hyperpigmentation are sun damage, scarring after inflammation of the skin (e.g acne, dermatitis, eczema), hormonal changes (melasma), drug-induced or disease related. Sun protection is a ‘must’ to prevent hyperpigmentation. In regards to treatment, hydroquinone still remains an important role. Hydroquinone (HQ) is a skin bleaching agent that inhibits the production of melanin which gives the skin its color. Recent studies have raised some question about its safety but it is considered as safe for short-term use...